Due to the low immune system of quarians, conception is much hard to achieve as even sexual cells perish at a much higher ratio. To compensate for this quarians females release several eggs for fertilization to increase the chance of conceiving. (This is non-canon and I can think of several biological reason why this would not be possible but a story needs a start).
With quarians it produces a birth rate similar to humans and no species has successfully breed across the species barrier with a quarian, but Shepard is the kind of Guy/Girl to be the first at many things and this could include making a quarian pregnant with several multiples.
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